He returned to action and was a constant fixture in the starting eleven and showed his impressive old form before the injury.He scored his second goal for Inter on 14 December against Chievo, which they won 4–2 after an assist from Dejan Stanković.

Maxwell played his best season for Ajax in the 2003–04 season, only missed three games for the Eredivisie winner due to international duty, and becoming the Dutch Footballer of the Year.

He was seriously injured in April 2005 before officially transferred to Inter in a similar deal to that of Júlio César to Chievo; however, he did not play any games.

In July 2006, Internazionale officially announced the signing of Maxwell on a four-year contract as a domestic transfer.

Maxwell impressed in his first season in Serie A, most notably against Parma at the San Siro when he scored a fine solo effort after a defender struck him which was voted Inter's thunder goal of the season by Inter channel viewers.

Maxwell started Barcelona's first competitive match of the 2010–11 season, the first leg of the 2010 Supercopa de España, in an advanced left-wing position; he assisted the opening goal for Zlatan Ibrahimović.

It was alleged that Maxwell registered as an EU player during 2006 to 2009 with Internazionale, but he was signed by Barcelona as a non-EU player (Brazil), as Maxwell did not present a passport from a European country.

UEFA started to investigate the case in August 2010, but in fact Inter signed him as a domestic transfer and he arrived in Italy as a non-EU player for Empoli, and had not violated Italian Football Federation (FIGC) regulations.

Initially playing at left-back, the 2007–08 season saw him move further up the field with Cristian Chivu replacing him at left-back while Maxwell played a left midfield role.

This became very effective as Maxwell adapted well to the winger role which made use of his blistering pace.